Topic: "antibody-design"
RosettaCommons/rosetta
The Rosetta Bio-macromolecule modeling package.
Language: C++ - Size: 1.73 GB - Last synced at: 5 days ago - Pushed at: 5 days ago - Stars: 297 - Forks: 101
oxpig/AntiFold
Improved antibody structure-based design using inverse folding
Language: Python - Size: 959 KB - Last synced at: 3 months ago - Pushed at: 3 months ago - Stars: 116 - Forks: 19
THUNLP-MT/dyMEAN
This repo contains the codes for our paper "End-to-End Full-Atom Antibody Design"
Language: Python - Size: 11.7 MB - Last synced at: 2 months ago - Pushed at: 5 months ago - Stars: 107 - Forks: 14
THUNLP-MT/MEAN
This repo contains the codes for our paper Conditional Antibody Design as 3D Equivariant Graph Translation.
Language: Python - Size: 16.8 MB - Last synced at: about 2 months ago - Pushed at: over 2 years ago - Stars: 95 - Forks: 16
AstraZeneca/DiffAbXL
The official implementation of DiffAbXL benchmarked in the paper "Exploring Log-Likelihood Scores for Ranking Antibody Sequence Designs", formerly titled "Benchmarking Generative Models for Antibody Design".
Language: Python - Size: 3.26 MB - Last synced at: about 2 months ago - Pushed at: about 2 months ago - Stars: 74 - Forks: 8
kxz18/UniMoMo
Codes for our paper "UniMoMo: Unified Generative Modeling of 3D Molecules for De Novo Binder Design" (ICML 2025)
Language: Python - Size: 1.28 MB - Last synced at: 2 months ago - Pushed at: 2 months ago - Stars: 24 - Forks: 2
yjcyxky/antibody-dl
A Collection of Platform, Tools, and Resources for Antibody Engineering
Language: Python - Size: 12.7 KB - Last synced at: 10 days ago - Pushed at: about 2 years ago - Stars: 17 - Forks: 6
TobiasHeOl/AbLang2
An antibody-specific language model focusing on NGL prediction
Language: Python - Size: 79.1 KB - Last synced at: 5 months ago - Pushed at: 5 months ago - Stars: 15 - Forks: 5
tommyhuangthu/SAAINT
structural antibody parser and database
Language: Python - Size: 105 MB - Last synced at: 1 day ago - Pushed at: 1 day ago - Stars: 9 - Forks: 1
AstraZeneca/SelfPAD
The official implementation of "Improving Antibody Humanness Prediction using Patent Data".
Language: Python - Size: 425 KB - Last synced at: 3 months ago - Pushed at: over 1 year ago - Stars: 9 - Forks: 4
futianfan/energy_model4antibody_design
Energy-based Model for Antibody Design
Language: Python - Size: 2.29 MB - Last synced at: almost 2 years ago - Pushed at: almost 2 years ago - Stars: 9 - Forks: 0
LLNL/protlib-designer
Integer Linear Programming for Protein Library Design
Language: Python - Size: 1.88 MB - Last synced at: 5 days ago - Pushed at: about 1 month ago - Stars: 6 - Forks: 0
tuplexyz/PD-1_Fab_Diffusion
PD-1 Targeted Antibody Discovery Using AI Protein Diffusion
Language: Shell - Size: 1.27 GB - Last synced at: 11 months ago - Pushed at: 11 months ago - Stars: 6 - Forks: 0
jbderoo/scFv_Pmpnn_AF2
Associated code/pipeline for the publication "AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications"
Language: Python - Size: 962 KB - Last synced at: 5 months ago - Pushed at: 5 months ago - Stars: 4 - Forks: 0
dohlee/diffab-pytorch
An unofficial re-implementation of DiffAb, a diffusion-based generative model for antigen-specific antibody design and optimization.
Language: Python - Size: 903 KB - Last synced at: 4 months ago - Pushed at: almost 2 years ago - Stars: 4 - Forks: 0
zarifikram/gg-dWJS
Gradient guided discrete walk-jump sampling
Language: Python - Size: 374 MB - Last synced at: 6 months ago - Pushed at: 6 months ago - Stars: 3 - Forks: 0
olakalisz/adios
Code for ADIOS: Antibody Development via Opponent Shaping
Language: Python - Size: 1.83 MB - Last synced at: 30 days ago - Pushed at: 30 days ago - Stars: 2 - Forks: 0
pgbarletta/locuaz
Antibody optimization platform
Language: Python - Size: 50.2 MB - Last synced at: 11 months ago - Pushed at: 12 months ago - Stars: 2 - Forks: 2
dohlee/protstruc
Protein structure handling in Python made easy.
Language: HTML - Size: 50.3 MB - Last synced at: 26 days ago - Pushed at: almost 2 years ago - Stars: 2 - Forks: 1
izgys/antibody-affinity-engineering
A computational pipeline for improving antibody-antigen binding affinity through CDR-focused mutations, using AI-based inverse folding (ProteinMPNN), structural modeling (IgFold, AlphaFold-Multimer), and binding affinity prediction with FoldX. Designed for antibody engineering and rational biologic design.
Size: 1.95 KB - Last synced at: 28 days ago - Pushed at: 28 days ago - Stars: 1 - Forks: 0
LirongWu/RAAD
Code for AAAI 2025 paper "Relation-Aware Equivariant Graph Networks for Epitope-Unknown Antibody Design and Specificity Optimization"
Language: C++ - Size: 13 MB - Last synced at: 3 months ago - Pushed at: 3 months ago - Stars: 1 - Forks: 0
naviret/rl_bnab_maturation_pathways
Characterizing Broadly Neutralizing Antibody Maturation Pathways Using Reinforcement Learning
Language: Python - Size: 28.1 MB - Last synced at: over 1 year ago - Pushed at: over 1 year ago - Stars: 1 - Forks: 0
partrita/CloneBO Fork of AlanNawzadAmin/CloneBO
진화하는 시퀀스의 생성 모델을 기반 항체 서열 최적화.
Language: Python - Size: 3.57 MB - Last synced at: 4 days ago - Pushed at: 4 days ago - Stars: 0 - Forks: 0
Nargaruga/antibody_evolution_wizard
PyMOL wizard integrating brianhie/efficient-evolution and haddocking/prodigy for guided antibody evolution.
Language: Python - Size: 200 KB - Last synced at: about 1 month ago - Pushed at: about 1 month ago - Stars: 0 - Forks: 0
deepbiolab/deepbiolab.github.io
DeepBioLab is an AI-focused platform designed to explore, build, and share advanced AI algorithms. It features educational content, projects, and research on topics like deep learning, reinforcement learning, and more. Dive into algorithms, develop from scratch, and discover solutions to science problems.
Language: HTML - Size: 90.7 MB - Last synced at: 4 months ago - Pushed at: 5 months ago - Stars: 0 - Forks: 0
johnnytam100/elmo1-rhog_nanobody_design
This repository contains codes for the regeneration of figures 3b and 3g in Tam, C., Kukimoto-Niino, M., Miyata-Yabuki, Y. et al. Targeting Ras-binding domain of ELMO1 by computational nanobody design. Commun Biol 6, 284 (2023).
Language: Jupyter Notebook - Size: 2.11 MB - Last synced at: almost 2 years ago - Pushed at: almost 2 years ago - Stars: 0 - Forks: 0
