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GitHub topics: epistasis

Cassie818/MsaPhylo

Learning the language of phylogeny with MSA Transformer

Language: Jupyter Notebook - Size: 40.3 MB - Last synced at: 2 days ago - Pushed at: 2 days ago - Stars: 2 - Forks: 0

EpistasisLab/PAGER

PAGER is an efficient genotype encoding strategy designed to improve the detection of non-additive genetic variation in complex trait association studies. PAGER dynamically encodes genetic variants by normalizing mean phenotypic differences between genotype classes.

Language: Python - Size: 531 KB - Last synced at: about 1 month ago - Pushed at: 5 months ago - Stars: 3 - Forks: 1

lcrawlab/sme

A fast and scalable method to detect epistasis in complex traits from biobank-scale studies

Language: C++ - Size: 3.25 MB - Last synced at: 5 days ago - Pushed at: 4 months ago - Stars: 1 - Forks: 0

harmslab/epistasis

A Python API for estimating statistical high-order epistasis in genotype-phenotype maps.

Language: Python - Size: 4.62 MB - Last synced at: about 1 month ago - Pushed at: almost 2 years ago - Stars: 34 - Forks: 11

lcrawlab/mvMAPIT

The multivariate MArginal ePIstasis Test

Language: R - Size: 37.8 MB - Last synced at: about 1 month ago - Pushed at: 7 months ago - Stars: 11 - Forks: 1

harmslab/gpseer

A tool to predict missing data in sparsely sampled genotype-phenotype maps

Language: Python - Size: 1.57 MB - Last synced at: 11 days ago - Pushed at: almost 2 years ago - Stars: 6 - Forks: 3

lcrawlab/i-LDSC

Code and simulations using interaction-LD score regression

Language: Python - Size: 15.4 GB - Last synced at: 6 months ago - Pushed at: 11 months ago - Stars: 12 - Forks: 1

thomasWeise/BBDOB_W_Model

The W-Model, a tunable Black-Box Discrete Optimization Benchmarking (BB-DOB) problem, implemented for the BB-DOB@GECCO Workshop.

Language: Java - Size: 155 KB - Last synced at: 18 days ago - Pushed at: over 4 years ago - Stars: 4 - Forks: 3

complexgenome/CUMC_taub

Language: R - Size: 374 KB - Last synced at: 11 months ago - Pushed at: over 3 years ago - Stars: 0 - Forks: 0

greenelab/model-free-data

Case-control genetics datasets evolved to be epistatic

Language: PostScript - Size: 13.9 MB - Last synced at: 2 days ago - Pushed at: almost 7 years ago - Stars: 5 - Forks: 2

pecanka/epidetector

EpiDetector: A tool for identifying epistasis

Language: Fortran - Size: 36 MB - Last synced at: about 1 year ago - Pushed at: over 3 years ago - Stars: 1 - Forks: 0

bglezseoane/pytoxo

A Python tool to calculate penetrance tables for high-order epistasis models

Language: Python - Size: 14 MB - Last synced at: 22 days ago - Pushed at: about 3 years ago - Stars: 2 - Forks: 0

Chester75321/GenEpi

A package for detecting epistasis by machine learning

Language: Python - Size: 11.8 MB - Last synced at: 17 days ago - Pushed at: 11 months ago - Stars: 20 - Forks: 9

UDC-GAC/mpi3snp

GWAS third-level epistatic search tool for cluster architectures

Language: C++ - Size: 552 KB - Last synced at: over 1 year ago - Pushed at: about 5 years ago - Stars: 2 - Forks: 0

amirmohan/epistatic-net

Epistatic Net is an algorithm which allows for spectral regularization of deep neural networks to predict biological fitness functions (e.g., protein functions).

Language: Jupyter Notebook - Size: 1.05 MB - Last synced at: over 1 year ago - Pushed at: almost 4 years ago - Stars: 15 - Forks: 2

lorinanthony/MAPIT

Code and Tutorials for Running the MArginal ePIstasis Test (MAPIT)

Language: C++ - Size: 65.4 KB - Last synced at: over 1 year ago - Pushed at: over 2 years ago - Stars: 11 - Forks: 3

insilico/npdr

NPDR: Nearest-neighbor Projected-Distance Regression with the generalized linear model

Language: R - Size: 24 MB - Last synced at: about 1 year ago - Pushed at: almost 2 years ago - Stars: 12 - Forks: 6

Zhengtong-Liu/CS-M226-Project

Non-linear Genetic Effects for Complex Traits

Language: Jupyter Notebook - Size: 22.6 MB - Last synced at: almost 2 years ago - Pushed at: over 2 years ago - Stars: 1 - Forks: 0

colbyford/parEBEN

Parallel Implementations of the Empirical Bayesian Elastic Net Cross-Validation in R

Language: C - Size: 107 MB - Last synced at: about 2 years ago - Pushed at: almost 3 years ago - Stars: 5 - Forks: 2

alexcis95/VARI3

Approach to VARIantVARIant interaction through VARIable thresholds and hypothesis testing. VARI3 automates the selection and analysis of the most promising SNPs to identify epistasis.

Language: R - Size: 92.8 KB - Last synced at: about 2 years ago - Pushed at: almost 3 years ago - Stars: 0 - Forks: 0

harmslab/notebooks-nonlinear-high-order-epistasis

Jupyter notebooks for Genetics paper, "Detecting high-order epistasis in nonlinear genotype-phenotype maps"

Language: Jupyter Notebook - Size: 3.47 MB - Last synced at: about 1 year ago - Pushed at: over 7 years ago - Stars: 6 - Forks: 11

UDC-GAC/toxo

A library for calculating penetrance tables of any bivariate epistasis model.

Language: MATLAB - Size: 129 KB - Last synced at: about 2 years ago - Pushed at: over 4 years ago - Stars: 1 - Forks: 2

xsitarcik/epiBAT

Language: Python - Size: 14.6 KB - Last synced at: about 2 years ago - Pushed at: over 5 years ago - Stars: 1 - Forks: 0

biolab/red

Inference of Epistatic Gene Networks

Language: Python - Size: 2.88 MB - Last synced at: about 1 year ago - Pushed at: over 10 years ago - Stars: 3 - Forks: 2

Zsailer/notebooks-nonlinear-high-order-epistasis Fork of harmslab/notebooks-nonlinear-high-order-epistasis

All materials and analysis as Jupyter notebooks for Genetics paper.

Language: Jupyter Notebook - Size: 3.47 MB - Last synced at: 3 months ago - Pushed at: over 7 years ago - Stars: 0 - Forks: 0

Related Keywords
epistasis 25 genetics 10 gwas 8 epistasis-analysis 4 gwas-tools 4 heritability 3 statistics 3 python 3 bioinformatics 3 r 3 snp 2 variance-components 2 linear-mixed-models 2 machine-learning 2 high-order 2 genotype-phenotype-maps 2 evolution 2 mapit 2 snps 2 simulation 2 cran 2 cpp 2 genetic-interactions 2 qtl-mapping 1 gwas-case-control 1 sparse-recovery 1 protein-function-prediction 1 deep-learning 1 threading 1 snp-genotyping 1 prevalence 1 parallelism 1 mpi 1 gpu 1 cuda 1 bat-algorithm 1 penetrance-tables 1 human-genome 1 full-genome 1 mutant-data 1 two-stage 1 testing 1 software 1 fortran 1 efficient 1 supplement 1 network-inference 1 jupyter-notebook 1 regression-models 1 regularization 1 high-order-epistasis 1 jupyter-notebooks 1 parallel 1 genomics 1 interaction-effect 1 elastic-nets 1 marchini 1 cross-validation 1 bayesian-inference 1 model 1 algorithm 1 penetrance-table 1 rna-seq 1 relief 1 projected-distances 1 nearest-neighbors 1 glm 1 genome-wide-data 1 gene-expression 1 feature-selection 1 eqtl 1 covariates 1 deterministic 1 combinatorial-optimization 1 black-box-benchmarking 1 benchmark-problem 1 benchmark 1 ld-score-regression 1 heritability-estimation 1 gwas-summary-statistics 1 prediction 1 genotype-phenotype-map 1 mvmapit 1 nonlinear 1 modeling 1 epistatis 1 qtl-analysis 1 non-additive-effects 1 heterosis 1 genotype-to-phenotype 1 genetic-inheritance 1 encoding 1 dominance-analysis 1 additive-models 1 protein-language-model 1 protein-evolution 1 phylogenetic-reconstruction 1 msa-transformer 1 interpretable-machine-learning 1 open-data 1