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GitHub topics: mendelian-randomization

remlapmot/mrdags

Code to draw DAG and SWIG figures for Mendelian randomization studies

Language: RMarkdown - Size: 16.7 MB - Last synced at: 8 days ago - Pushed at: 9 days ago - Stars: 4 - Forks: 0

SidSin0809/forestplotR

Journal-ready forest plots with uniform spacing, embedded fonts, and automated sizing for Mendelian-randomization (or any β/CI) results.

Language: R - Size: 15.6 KB - Last synced at: 9 days ago - Pushed at: 9 days ago - Stars: 0 - Forks: 0

MRCIEU/opengwas-api

API for MRC-IEU OpenGWAS

Language: Python - Size: 21.3 MB - Last synced at: 11 days ago - Pushed at: 12 days ago - Stars: 5 - Forks: 2

remlapmot/ivonesamplemr

Stata package for one-sample Mendelian randomization / instrumental variable analyses

Language: Stata - Size: 3.48 MB - Last synced at: 3 days ago - Pushed at: about 1 month ago - Stars: 2 - Forks: 1

remlapmot/mrrobust

Stata package for two-sample Mendelian randomization analyses using summary data

Language: Stata - Size: 7.86 MB - Last synced at: 3 days ago - Pushed at: about 1 month ago - Stars: 23 - Forks: 8

remlapmot/bpbounds

R package implementing nonparametric bounds for the ACE due to Balke and Pearl, JASA, 1997

Language: R - Size: 5.93 MB - Last synced at: 1 day ago - Pushed at: about 1 month ago - Stars: 0 - Forks: 1

remlapmot/OneSampleMR

R package of useful functions for one-sample Mendelian randomization and instrumental variable analyses

Language: R - Size: 8.39 MB - Last synced at: 21 days ago - Pushed at: 22 days ago - Stars: 19 - Forks: 3

OpenOmics/mr-seek

Mendelian Randomization pipeline

Language: Python - Size: 749 KB - Last synced at: 2 months ago - Pushed at: 2 months ago - Stars: 2 - Forks: 1

molepi-precmed/mrhevo

Inference of causal effects by Mendelian randomization, marginalizing over distribution of direct effects

Language: HTML - Size: 1.06 MB - Last synced at: 3 months ago - Pushed at: 3 months ago - Stars: 0 - Forks: 0

shanecrinion/causal-inference

Mendelian randomisation analysis using GWAS data for neuropsychiatric disorders and chronotype to assess their bidirectional causal relationship.

Language: R - Size: 1.29 MB - Last synced at: 3 months ago - Pushed at: almost 4 years ago - Stars: 2 - Forks: 1

ht-diva/MR_instruments_selection

Language: R - Size: 681 KB - Last synced at: 3 months ago - Pushed at: 3 months ago - Stars: 0 - Forks: 0

grnlab/airqtl

Single-cell eQTL mapping and causal gene regulatory network inference at high efficiency and accuracy

Language: Python - Size: 68.4 KB - Last synced at: 7 days ago - Pushed at: 4 months ago - Stars: 1 - Forks: 1

MRCIEU/epigraphdb-r

R package for epigraphdb

Language: R - Size: 5.88 MB - Last synced at: 17 days ago - Pushed at: 11 months ago - Stars: 27 - Forks: 8

SamuelMathieu-code/LaScaMolMR.jl

A molecular Mendelian Randomization tool

Language: Julia - Size: 506 KB - Last synced at: 9 months ago - Pushed at: 9 months ago - Stars: 0 - Forks: 0

mikelove/mrlocus

Older repo for MRLocus. See new website for software usage guide:

Language: R - Size: 3.31 MB - Last synced at: 2 months ago - Pushed at: almost 2 years ago - Stars: 15 - Forks: 8

rittata/PD_and_GI_diseases_MR

Coursework project on Mendelian randomisation analysis for several gastrointestinal diseases and Parkinson's disease risk and progression.

Language: R - Size: 17.6 KB - Last synced at: 11 months ago - Pushed at: 11 months ago - Stars: 1 - Forks: 0

mvab/mammographic_density_mr

MR project investigating the mediating role of mammographic density in the childhood body size and breast cancer relationship

Language: R - Size: 5.4 MB - Last synced at: about 1 year ago - Pushed at: about 1 year ago - Stars: 6 - Forks: 0

mvab/mendelian-randomization-breast-cancer

Analysis workflow for MRC-IEU PhD mini-project on childhood BMI effect on breast cancer

Language: R - Size: 16.1 MB - Last synced at: about 1 year ago - Pushed at: about 1 year ago - Stars: 57 - Forks: 20

NCBI-Hackathons/MR_BACOn

Mendelian Randomization with Biomarker Associations for Causality with Outcomes

Language: R - Size: 29 MB - Last synced at: about 1 year ago - Pushed at: over 6 years ago - Stars: 22 - Forks: 9

mboissel/MR_training

Starter Pack About Mendelian Randomization. My Feedback about MR traning followed in 2020.

Language: HTML - Size: 71.2 MB - Last synced at: over 1 year ago - Pushed at: over 1 year ago - Stars: 2 - Forks: 0

ash-res/focused-MR

R code to reproduce results of data examples in 'Selecting invalid instruments to improve MR with two-sample summary data''

Language: R - Size: 184 KB - Last synced at: over 1 year ago - Pushed at: over 1 year ago - Stars: 0 - Forks: 1

lindgrengroup/obesity_femrepr_MR

Code for analyses in "Obesity and risk of female reproductive disorders: A Mendelian Randomisation Study"

Language: R - Size: 569 KB - Last synced at: over 1 year ago - Pushed at: over 3 years ago - Stars: 8 - Forks: 1

bakulskilab/Dyslipidemia_Dementia_MR

Mendelian Randomization of Dyslipidemia on Cognitive Impairment Among Older Americans

Language: R - Size: 26.4 KB - Last synced at: over 1 year ago - Pushed at: over 2 years ago - Stars: 0 - Forks: 1

bakulskilab/Diabetes_Dementia_MR

Type 2 diabetes and dementia in the Health and Retirement Study: A Mendelian randomization approach

Language: R - Size: 26.4 KB - Last synced at: over 1 year ago - Pushed at: over 2 years ago - Stars: 5 - Forks: 2

ACDBio/AutoMR

An R script to perform two sample Mendelian randomization screening (with TwoSampleMR) for a custom summary statistic against a set of summary statistics from the IEU GWAS database.

Language: R - Size: 6.52 MB - Last synced at: almost 2 years ago - Pushed at: over 2 years ago - Stars: 19 - Forks: 1

YangLabHKUST/MRAPSS_RealDataAnalysis_reproduce

R code for reproduce real data analysis in MRAPSS paper.

Language: HTML - Size: 6.15 MB - Last synced at: almost 2 years ago - Pushed at: about 3 years ago - Stars: 1 - Forks: 0

jiazhao97/BWMR

BWMR (Bayesian Weighted Mendelian Randomization)

Language: R - Size: 244 KB - Last synced at: almost 2 years ago - Pushed at: almost 2 years ago - Stars: 10 - Forks: 1

pasted/gw_meta_analysis_low_muscle_strength 📦

Analysis code and processing stages for Genome-Wide meta-analysis of low grip strength in older people.

Language: R - Size: 26.4 KB - Last synced at: about 2 years ago - Pushed at: over 4 years ago - Stars: 4 - Forks: 0

CTLife/xQTLs

Scripts for various molecular quantitative trait locus (xQTL) analysis.

Language: Perl - Size: 13.8 MB - Last synced at: about 2 years ago - Pushed at: over 2 years ago - Stars: 2 - Forks: 0

adriaan-vd-graaf/genome_integration

MR-link and genome integration. genome_integration is a repository for the analysis of genomic data. Specifically, the repository implements the causal inference method MR-link, as well as other Mendelian randomization methods.

Language: Python - Size: 4.43 MB - Last synced at: over 2 years ago - Pushed at: almost 3 years ago - Stars: 7 - Forks: 0

masadler/smrivw Fork of jianyangqt/smr

SMR-IVW extension of the SMR software

Language: C++ - Size: 3.44 MB - Last synced at: about 2 years ago - Pushed at: about 2 years ago - Stars: 2 - Forks: 3

ellenmartin11/lone-GenSEM-MR

Genomic Structural Equation Modelling and Mendelian Randomization of Loneliness and Psychiatric/Substance Use Phenotypes

Language: Shell - Size: 698 KB - Last synced at: over 2 years ago - Pushed at: over 2 years ago - Stars: 4 - Forks: 0

lf-araujo/mr-doc2

Original repository for the paper MR-DoC2, however there is a custom function implemented in the R package umx()

Language: R - Size: 7.81 KB - Last synced at: about 2 years ago - Pushed at: about 3 years ago - Stars: 0 - Forks: 0

remlapmot/mr2019-tom-palmer-poster

Poster for Mendelian randomization conference 2019

Language: TeX - Size: 8.32 MB - Last synced at: 3 days ago - Pushed at: over 3 years ago - Stars: 0 - Forks: 0

adRn-s/ukbbgwas

Explore SNVs associated with any of UK BioBank Phenotypes, results were made publicly available by: http://www.nealelab.is/uk-biobank

Language: R - Size: 2.48 MB - Last synced at: 2 days ago - Pushed at: over 3 years ago - Stars: 0 - Forks: 0

rivas-lab/regularizedMR

MR using L1 penalty

Language: R - Size: 9.77 KB - Last synced at: over 2 years ago - Pushed at: over 5 years ago - Stars: 0 - Forks: 0

Related Keywords
mendelian-randomization 36 r 9 gwas 8 mendelian-randomisation 6 mendelianrandomisation 6 causal-inference 6 mendelianrandomization 6 mr 5 genetics 4 instrumental-variable 4 qtl 3 genomics 3 epidemiology 3 bioinformatics 3 gwas-summary-statistics 3 instrumental-variables 3 stata 2 iv 2 pleiotropy 2 eqtl 2 snakemake 2 meta-analysis 2 causality 2 causality-analysis 2 dementia 2 female-reproductive-disease 1 metabolites 1 dyslipidemia 1 diabetes 1 genomics-data 1 correlated-pleiotropy 1 inside 1 obesity 1 selection-bias 1 ageing-well 1 gwas-pipeline 1 biomarkers 1 associations 1 mediation-analysis 1 multiomics 1 lasso 1 ukbiobank 1 manhattan-plot 1 posterdown 1 mrconf19 1 statistics 1 openmx 1 structural-equation-modeling 1 psychology 1 loneliness 1 depression 1 omics 1 simulate-phenotypes 1 gene-expression 1 causality-algorithms 1 causal-phenotypes 1 causal-gene-expression 1 s-qtl 1 python 1 perl 1 m6a-qtl 1 human-brain 1 e-qtl 1 covariates-and-confounders 1 apa-qtl 1 pearl 1 nonparametric-bounds 1 nonparametric 1 mendelian 1 bounds 1 average-causal-effect 1 ace 1 two-sample 1 mr-egger 1 summary-statistics 1 population-genetics 1 tidyverse 1 svg 1 reproducible-research 1 patchwork 1 ggplot2 1 forest-plots 1 data-visualizations 1 swig 1 single-world-intervention-graph 1 directed-acyclic-graph 1 dags 1 phenotypes 1 graph-database 1 api-client 1 single-cell-multiomics 1 scrna-seq-analysis 1 gene-regulatory-network 1 eqtl-mapping 1 snakemake-pipeline 1 pqtl 1 interval 1 two-sample-mendelian-randomization 1 schizophrenia 1 regression 1