An open API service providing repository metadata for many open source software ecosystems.

GitHub topics: cell-cell-communication

sqjin/CellChat 📦

R toolkit for inference, visualization and analysis of cell-cell communication from single-cell data

Language: R - Size: 45.4 MB - Last synced at: 1 day ago - Pushed at: over 1 year ago - Stars: 699 - Forks: 157

saeyslab/nichenetr

NicheNet: predict active ligand-target links between interacting cells

Language: R - Size: 152 MB - Last synced at: 1 day ago - Pushed at: 5 days ago - Stars: 540 - Forks: 125

multitalk/awesome-cell-cell-communication

Collection of computational tools for cell-cell communication inference for single-cell and spatially resolved omics

Language: Jupyter Notebook - Size: 17.6 MB - Last synced at: 4 days ago - Pushed at: 19 days ago - Stars: 49 - Forks: 7

theislab/ncem

Learning cell communication from spatial graphs of cells

Language: Python - Size: 40.8 MB - Last synced at: about 17 hours ago - Pushed at: over 1 year ago - Stars: 110 - Forks: 14

jinworks/CellChat

R toolkit for inference, visualization and analysis of cell-cell communication from single-cell and spatially resolved transcriptomics

Language: R - Size: 71.5 MB - Last synced at: 9 days ago - Pushed at: about 2 months ago - Stars: 403 - Forks: 68

ZJUFanLab/SpaTalk

Knowledge-graph-based cell-cell communication inference for spatially resolved transcriptomic data

Language: R - Size: 9.83 MB - Last synced at: 4 days ago - Pushed at: 4 months ago - Stars: 71 - Forks: 18

saezlab/liana-py

LIANA+: an all-in-one framework for cell-cell communication

Language: Python - Size: 272 MB - Last synced at: 7 days ago - Pushed at: 4 months ago - Stars: 206 - Forks: 25

saezlab/liana

LIANA: a LIgand-receptor ANalysis frAmework

Language: R - Size: 82.3 MB - Last synced at: 12 days ago - Pushed at: 10 months ago - Stars: 202 - Forks: 34

multitalk/miRTalk

Extracellular vesicle-derived miRNA-mediated cell-cell communication inference for single-cell transcriptomic data

Language: HTML - Size: 77 MB - Last synced at: 4 days ago - Pushed at: about 2 months ago - Stars: 14 - Forks: 2

StatBiomed/SpatialDM

Spatial direct messaging detected by bivariate Moran

Language: Jupyter Notebook - Size: 51.1 MB - Last synced at: 22 days ago - Pushed at: about 1 month ago - Stars: 26 - Forks: 6

saeyslab/multinichenetr

MultiNicheNet: a flexible framework for differential cell-cell communication analysis from multi-sample multi-condition single-cell transcriptomics data

Language: HTML - Size: 686 MB - Last synced at: about 1 month ago - Pushed at: 5 months ago - Stars: 144 - Forks: 17

multitalk/scCrossTalk

Infer and visualize cell-cell communication for single-cell RNA-seq data

Language: HTML - Size: 50.3 MB - Last synced at: 4 days ago - Pushed at: 5 months ago - Stars: 6 - Forks: 1

earmingol/cell2cell

User-friendly tool to infer cell-cell interactions and communication from gene expression of interacting proteins

Language: Python - Size: 99.7 MB - Last synced at: 28 days ago - Pushed at: 12 months ago - Stars: 60 - Forks: 17

ZJUFanLab/CellTalkDB

A manually curated database of literature-supported ligand-receptor interactions in human and mouse

Language: R - Size: 18.5 MB - Last synced at: 4 days ago - Pushed at: 11 months ago - Stars: 30 - Forks: 5

JEFworks-Lab/MERINGUE

characterizing spatial gene expression heterogeneity in spatially resolved single-cell transcriptomics data with nonuniform cellular densities

Language: R - Size: 89.8 MB - Last synced at: 2 months ago - Pushed at: almost 3 years ago - Stars: 69 - Forks: 5

CostaLab/CrossTalkeR

R package to do the Ligand Receptor Analysis Visualization

Language: Jupyter Notebook - Size: 173 MB - Last synced at: about 1 month ago - Pushed at: about 1 month ago - Stars: 42 - Forks: 10

Svvord/FastCCC

A permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single cell transcriptomics studies

Language: Jupyter Notebook - Size: 22.1 MB - Last synced at: 4 days ago - Pushed at: 3 months ago - Stars: 5 - Forks: 1

ChanghanGitHub/exFINDER

Identifying external communication signals using single-cell transcriptomics data

Language: HTML - Size: 270 MB - Last synced at: about 1 month ago - Pushed at: 12 months ago - Stars: 20 - Forks: 1

SunXQlab/scMLnet

Single-cell RNA-seq data-based inference of multilayer inter- and intra-cellular signaling networks

Language: R - Size: 12.9 MB - Last synced at: about 1 month ago - Pushed at: almost 4 years ago - Stars: 26 - Forks: 8

skimlab/spatialCCC

Investigate cell-cell signaling, by analyzing ligand-receptor interactions in spatial transcriptomic data

Language: HTML - Size: 74 MB - Last synced at: 6 months ago - Pushed at: 6 months ago - Stars: 1 - Forks: 1

liuyifang/FlyPhoneDB

Source code for Liu, Y., Li, J. S. S., Rodiger, J., Comjean, A., Attrill, H., Antonazzo, G., ... & Perrimon, N. (2022). FlyPhoneDB: an integrated web-based resource for cell–cell communication prediction in Drosophila. Genetics, 220(3), iyab235.

Language: R - Size: 3.15 MB - Last synced at: about 2 months ago - Pushed at: 11 months ago - Stars: 6 - Forks: 7

LitingKu/SpaCCI

SpaCCI: Spatially Aware Cell-Cell Interaction Analysis

Language: R - Size: 15.7 MB - Last synced at: 7 months ago - Pushed at: 8 months ago - Stars: 0 - Forks: 0

lhc17/HoloNet

HoloNet. Reveal the holograph of functional communication events in spatial transcriptomics. Help understand how microenvironments shaping cellular phenotypes

Language: Python - Size: 6.47 MB - Last synced at: about 1 month ago - Pushed at: 9 months ago - Stars: 21 - Forks: 3

dalodriguez/ExPCom

Differential communication analysis for scRNAseq datasets based on expression products

Language: R - Size: 41.1 MB - Last synced at: 10 months ago - Pushed at: 10 months ago - Stars: 0 - Forks: 0

lasseignelab/230313_TS_CCCinHumanAD

This repo accompanies the Soelter et al., 2024 manuscript "Altered Glia-Neuron Communication in Alzheimer’s Disease Affects WNT, p53, and NFkB Signaling Determined by snRNA-seq"

Language: R - Size: 1.1 GB - Last synced at: 4 months ago - Pushed at: 12 months ago - Stars: 1 - Forks: 1

Jia-Zhao1998/20.440-Group_Project_JZ_APM

20.440 Group Project-Intercellular Communication in vivo

Language: Jupyter Notebook - Size: 31.6 MB - Last synced at: about 1 year ago - Pushed at: about 1 year ago - Stars: 0 - Forks: 0

saezlab/ccc_protocols

LIANA x Tensor-cell2cell Protocols

Language: Jupyter Notebook - Size: 168 MB - Last synced at: about 2 months ago - Pushed at: about 1 year ago - Stars: 1 - Forks: 3

SunXQlab/ESICCC

ESICCC: A systematic computational framework for evaluation, selection and integration of cell-cell communication inference methods

Language: R - Size: 23.4 MB - Last synced at: over 1 year ago - Pushed at: over 1 year ago - Stars: 11 - Forks: 1

theimagelab/entrain

Entrain: Predicting Environmental Regulators of Differentiation Trajectories

Language: R - Size: 63.9 MB - Last synced at: over 1 year ago - Pushed at: over 1 year ago - Stars: 2 - Forks: 0

WangShuxiong/SoptSC

SoptSC for single cell data analysis: unsupervised inference of clustering, cell lineage, pseudotime and cell-cell communication network from scRNA-seq data.

Language: MATLAB - Size: 62 MB - Last synced at: over 1 year ago - Pushed at: over 4 years ago - Stars: 19 - Forks: 5

ZJUFanLab/SpaTrio

Language: Python - Size: 74.5 MB - Last synced at: over 1 year ago - Pushed at: over 1 year ago - Stars: 4 - Forks: 1

auroramaurizio/periferal_nerve_injury

Bioinfo scripts for the analyses described in EXPERIMENTAL PROCEDURES section of "Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve" manuscript

Language: Jupyter Notebook - Size: 19.4 MB - Last synced at: 10 months ago - Pushed at: about 1 year ago - Stars: 0 - Forks: 2

ZJUFanLab/scDeepTalk

Infer cell-cell communications based on feed-forward neural network

Language: R - Size: 14.4 MB - Last synced at: 4 days ago - Pushed at: over 4 years ago - Stars: 3 - Forks: 0

ccruizm/GBmap

Code used to create the core and extended GBmap, including downstream analyses (cell-cell interactions, spatial transcriptomics deconvolution) and how to produce the figures.

Language: Jupyter Notebook - Size: 98.8 MB - Last synced at: over 2 years ago - Pushed at: over 2 years ago - Stars: 9 - Forks: 0

SunXQlab/scMLnet2.0 Fork of YUZIXD/scMLnet2.0

scMLnet2.0: Single-cell RNA-seq data-based inference of multilayer inter- and intra-cellular signaling networks

Size: 15 MB - Last synced at: about 2 years ago - Pushed at: almost 4 years ago - Stars: 0 - Forks: 0

hmbaghdassarian/c2c_sim

Pipeline for simulating CCI dynamics across time

Language: Jupyter Notebook - Size: 12.8 MB - Last synced at: about 2 years ago - Pushed at: over 2 years ago - Stars: 0 - Forks: 0

Related Keywords
cell-cell-communication 36 cell-cell-interaction 13 single-cell 11 single-cell-rna-seq 11 spatial-transcriptomics 10 ligand-receptor 6 single-cell-analysis 5 ligand-receptor-interaction 5 bioinformatics 4 microenvironment 3 rna-seq 3 single-cell-omics 3 intercellular-signaling 2 scrna-seq 2 liana 2 tensor-decomposition 2 python 2 gene-regulation 2 spatial-data-analysis 2 ligand-target 2 intercellular-communication 2 gene-expression 2 intracellular-regulations 1 benchmarking 1 benchmark 1 single-cell-rna-sequencing 1 spatial-relationships 1 tensor-cell2cell 1 tissue-resident-macrophages 1 nichenet 1 computational-alghoritms 1 adipose-tissue 1 neurodegenerative-diseases 1 alzheimers-disease 1 transcriptomics 1 visium-st 1 spot-level 1 single-cell-transcriptomics 1 external-signals 1 simulation 1 multilayer-networks 1 inter--and-intra-cellular-signaling 1 large-scale-data-analytics 1 glioblastoma 1 feed-forward-neural-networks 1 deep-learning 1 velocity 1 pseudotime 1 nerve 1 injury 1 deconvolution 1 bulkrnaseq 1 spatial-omics 1 single-cell-multi-omics 1 soptsc 1 optimization-algorithms 1 nmf 1 trajectory-analysis 1 rna-velocity 1 differentiation 1 cell-fate 1 scrna-seq-analysis 1 extracellular-vesicles 1 exosomes 1 omnipath 1 cellphonedb 1 cellchat 1 spatialomics 1 spatial 1 spatially-resolved-transcriptomics 1 knowledge-graph 1 graph-network 1 tensorflow 1 squidpy 1 scanpy 1 gnn 1 glm 1 encoder-decoder-model 1 cvae 1 transcriptomics-data 1 network-inference 1 data-integration 1 permutation-free 1 human-ccc-reference-panel 1 fastccc 1 network 1 spatial-analysis 1 rstats 1 toolkit 1 database 1 data-analysis 1 sc-rna-seq 1 rnaseq 1 machine-learning 1 computational-biology 1 bulk-rna-seq 1 systems-biology 1 differential-expression 1 spatial-correlation 1 scrna-seq-data 1