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GitHub topics: tumor-heterogeneity

lima1/PureCN

Copy number calling and variant classification using targeted short read sequencing

Language: R - Size: 19 MB - Last synced at: 4 days ago - Pushed at: 4 days ago - Stars: 134 - Forks: 33

HautaniemiLab/jellyfisher

R htmlwidget for Jellyfish

Language: R - Size: 2.45 MB - Last synced at: 9 days ago - Pushed at: about 2 months ago - Stars: 4 - Forks: 0

AntonioDeFalco/SCEVAN

R package that automatically classifies the cells in the scRNA data by segregating non-malignant cells of tumor microenviroment from the malignant cells. It also infers the copy number profile of malignant cells, identifies subclonal structures and analyses the specific and shared alterations of each subpopulation.

Language: HTML - Size: 63 MB - Last synced at: 19 days ago - Pushed at: 19 days ago - Stars: 100 - Forks: 25

HautaniemiLab/jellyfish

Jellyfish plots for integrative visualization of spatio-temporal tumor evolution and clonal dynamics

Language: TypeScript - Size: 533 KB - Last synced at: 8 days ago - Pushed at: about 1 month ago - Stars: 2 - Forks: 0

gavinha/TitanCNA

Analysis of subclonal copy number alterations (CNA) and loss of heterozygosity (LOH) in cancer

Language: R - Size: 10.6 MB - Last synced at: 14 days ago - Pushed at: almost 4 years ago - Stars: 97 - Forks: 36

RichardObi/ccnet

Official repository of "Towards Learning Contrast Kinetics with Multi-Condition Latent Diffusion Models"

Language: Python - Size: 30.3 MB - Last synced at: 3 months ago - Pushed at: 3 months ago - Stars: 4 - Forks: 1

ChongQingNoSubway/DGR-MIL

Code for paper: DGR-MIL: Exploring Diverse Global Representation in Multiple Instance Learning for Whole Slide Image Classification [ECCV 2024]

Language: Python - Size: 2.29 MB - Last synced at: 4 months ago - Pushed at: 4 months ago - Stars: 128 - Forks: 4

its-Pa1/2D_Hypoxia_Modeling

This repository contains the codes for the article: Data-driven mechanistic modeling of oxygen distribution and hypoxia profile in tumor microenvironment

Language: MATLAB - Size: 147 MB - Last synced at: 10 months ago - Pushed at: 10 months ago - Stars: 0 - Forks: 0

paoloinglese/ion_colocalization

Scripts used for the paper Inglese, P., Correia, G., Pruski, P., Glen, R. C., & Takats, Z. (2019). Colocalization features for classification of tumors using desorption electrospray ionization mass spectrometry imaging. Analytical chemistry.

Language: R - Size: 68.4 KB - Last synced at: about 1 year ago - Pushed at: over 4 years ago - Stars: 1 - Forks: 0

emosca-cnr/scMuffin

scMuffin - A MUlti-Features INtegrative approach for SC data analysis

Language: R - Size: 78.3 MB - Last synced at: about 1 year ago - Pushed at: about 1 year ago - Stars: 2 - Forks: 0

KChen-lab/SiFit

Reconstructing phylogenetic tree from noisy mutation profile of single cells

Size: 24.7 MB - Last synced at: over 1 year ago - Pushed at: almost 6 years ago - Stars: 2 - Forks: 2

cansysbio/HGSOC_TME_Heterogeneity

Analysis of treatment naive and neo-adjuvant chemotherapy treated high-grade serous ovarian cancer samples

Language: Jupyter Notebook - Size: 132 MB - Last synced at: over 1 year ago - Pushed at: almost 5 years ago - Stars: 5 - Forks: 5

CMUSchwartzLab/BrM-Phylo

Phylogenies of Breast Cancer Brain Metastases

Language: Python - Size: 5.17 MB - Last synced at: over 1 year ago - Pushed at: over 5 years ago - Stars: 3 - Forks: 0

zhouzilu/DENDRO

Genetic Heterogeneity Profiling by Single Cell RNA Sequencing

Language: R - Size: 20.5 MB - Last synced at: over 1 year ago - Pushed at: almost 5 years ago - Stars: 30 - Forks: 6

nriddiford/svSupport

A tool to find reads supporting/opposing structural variant breakpoints

Language: Python - Size: 2.57 MB - Last synced at: over 1 year ago - Pushed at: about 4 years ago - Stars: 2 - Forks: 1

jasa-acs/Bayesian-Hierarchical-Varying-sparsity-Regression-Models-with-Application-to-Cancer-Proteogenomics

Reproducibility materials for "Bayesian Hierarchical Varying-sparsity Regression Models with Application to Cancer Proteogenomics" by Yang Ni, Francesco C. Stingo, Min Jin Ha, Rehan Akbani & Veerabhadran Baladandayuthapani

Language: Matlab - Size: 157 KB - Last synced at: over 1 year ago - Pushed at: over 6 years ago - Stars: 2 - Forks: 2

munozalexander/Tumor-Heterogeneity

Assessing tumor heterogeneity in bulk tumor DNA. Simulation of reads from a phylogenetic prior.

Language: Jupyter Notebook - Size: 13.1 MB - Last synced at: over 1 year ago - Pushed at: almost 8 years ago - Stars: 0 - Forks: 0

algo-cancer/PhISCS-BnB

A Fast Branch and Bound Algorithm for the Perfect Tumor Phylogeny Reconstruction Problem

Language: Python - Size: 11.8 MB - Last synced at: about 1 year ago - Pushed at: over 4 years ago - Stars: 8 - Forks: 3

FunGeST/Palimpsest

An R package for studying mutational signatures and structural variant signatures along clonal evolution in cancer.

Language: R - Size: 58.2 MB - Last synced at: over 1 year ago - Pushed at: almost 4 years ago - Stars: 67 - Forks: 19

CMUSchwartzLab/RAD

Robust and Accurate Deconvolution

Language: Jupyter Notebook - Size: 111 KB - Last synced at: over 1 year ago - Pushed at: over 4 years ago - Stars: 9 - Forks: 2

ratschlab/secedo

Clustering tumor cells based on SNVs from single-cell sequencing data

Language: C++ - Size: 9.21 MB - Last synced at: almost 2 years ago - Pushed at: almost 3 years ago - Stars: 6 - Forks: 0

spectre-team/spectre 📦

This project provides an Spectre's implementation of Data Mining Group's algorithms for processing mass spectrometry imaging (MSI) datasets.

Language: TypeScript - Size: 125 MB - Last synced at: over 1 year ago - Pushed at: over 6 years ago - Stars: 2 - Forks: 1

zengliX/SIFA

SIFA: identify tumor subclones and infer phylogenetic tree from WGS data

Language: R - Size: 2.16 MB - Last synced at: about 2 years ago - Pushed at: almost 7 years ago - Stars: 3 - Forks: 0

KChen-lab/Texomer

Texomer: Integrating Analysis of Cancer Genome and Transcriptome Sequencing Data

Language: R - Size: 32.9 MB - Last synced at: almost 2 years ago - Pushed at: over 4 years ago - Stars: 19 - Forks: 8

danieldanciu/secedo-experiments

Experiments for evaluating SECEDO, clustering tumor cells based on single cell sequencing data

Language: Jupyter Notebook - Size: 207 KB - Last synced at: about 2 years ago - Pushed at: about 3 years ago - Stars: 0 - Forks: 0

mostafa20223/GP

This repo is for "Tumor Heterogeneity - Graduation Project"

Language: Jupyter Notebook - Size: 409 MB - Last synced at: about 2 years ago - Pushed at: over 3 years ago - Stars: 0 - Forks: 0

alexandrutomescu/SNV-PPILP

Refined SNV calling for tumor data using perfect phylogenies and ILP

Language: Python - Size: 2.15 MB - Last synced at: about 2 years ago - Pushed at: about 6 years ago - Stars: 0 - Forks: 0

Related Keywords
tumor-heterogeneity 27 bioinformatics 7 tumor-evolution 7 single-cell 6 cancer-genomics 4 genomics 4 structural-variation 2 nmf 2 tumor-classification 2 subclone-identification 2 matrix-factorization 2 deconvolution 2 somatic-variants 2 copy-number-variation 2 visualization-tool 2 r 2 phylogenetic-analysis 2 mass-spectrometry-imaging 2 sam 1 dna-sequencing 1 threshold 1 prognostic-biomarkers 1 precision-medicine 1 p-splines 1 whole-genome-sequencing 1 tumor-segmentation 1 allele-frequencies 1 statistics 1 computational-biology 1 phylogenies 1 cancer 1 rna-seq 1 phylogenetic-trees 1 breast-cancer 1 tumor-microenvironment 1 transcriptomics 1 single-cell-genomics 1 ovarian-cancer 1 machine-learning 1 tcga-data 1 statistical-inference 1 functional-variants 1 bayesian-inference 1 proteomics 1 pattern-recognition 1 msi 1 gaussian-mixture-models 1 clustering 1 classification 1 rad 1 visualization 1 structural-variant-signatures 1 somatic-mutations 1 signature-extraction 1 nmf-extraction 1 mutational-signatures 1 driver-events 1 clonality 1 cancer-research 1 bioinformatics-analysis 1 sequencing 1 phylogeny 1 phylogenomics 1 mass-spectrometry 1 generative-ai 1 diffusion-models 1 dce-mri 1 controlnet 1 contrast-enhancement 1 contrast-agents 1 computer-vision 1 cancer-detection 1 hmm 1 genome-sequencing 1 10x-genomics 1 subclonal-deconvolution 1 scrna-seq-analysis 1 scrna-seq 1 scrna-pipeline 1 microenvironment 1 copynumber 1 clonal-evolution 1 clonal-analysis 1 aneuploidy 1 tumor-purity 1 tumor-mutational-burden 1 loh 1 copy-number 1 cell-free-dna 1 bioconductor-package 1 desi 1 reaction-diffusion-model 1 oxygen 1 mechanistic-modeling 1 image-processing 1 hypoxia 1 finite-difference-method 1 elliptic-pdes 1 whole-slide-imaging 1 weakly-supervised-learning 1